Publications
2025

T. Onodera, M.M. Stein, B.A. Ash, M.M. Sohoni, M. Bosch, R. Yanagimoto, T. Wang, G. Shvets, M.R. Shcherbakov, L.G. Wright, P.L. McMahon
Arbitrary control over multimode wave propagation for machine learning
Nature Physics 22, 164 - 171 (2025) | arXiv | codebase | dataset
Arbitrary control over multimode wave propagation for machine learning
Nature Physics 22, 164 - 171 (2025) | arXiv | codebase | dataset

S. Lee, S. Ghajari, S. Sadeghi, Y. Zheng, H. Zahr, A.J. Cortese, W. Gu, K. Choe, A. Mok, M. Wallace, R. Jiao, C. Wu, J.C. Werth, W. Fan, P. Mogalipuvvu, J.U. Park, S. Zhao, C. Smart, T.A. Cleland, M.R. Warden, J. Lammerding, T. Wang, J.H. Goldberg, P.L. McEuen, C. Xu, A.C. Molnar
A subnanolitre tetherless optoelectronic microsystem for chronic neural recording in awake mice
Nature Electronics 8, 1259 - 1271 (2025)
A subnanolitre tetherless optoelectronic microsystem for chronic neural recording in awake mice
Nature Electronics 8, 1259 - 1271 (2025)

The MICrONS Consortium. J.A. Bae, ... C. Zhang
Functional connectomics spanning multiple areas of mouse visual cortex
Nature 640, 435 - 447 (2025) | bioRxiv | dataset
Functional connectomics spanning multiple areas of mouse visual cortex
Nature 640, 435 - 447 (2025) | bioRxiv | dataset

S.-Y. Ma, T. Wang, J. Laydevant, L.G. Wright, P.L. McMahon
Quantum-limited stochastic optical neural networks operating at a few quanta per activation
Nature Communications 16, 359 (2025) | arXiv | codebase
Quantum-limited stochastic optical neural networks operating at a few quanta per activation
Nature Communications 16, 359 (2025) | arXiv | codebase
L. Abou-Hamdan, E. Marinov, P. Wiecha, P. del Hougne, T. Wang, P. Genevet
Programmable metasurfaces for future photonic artificial intelligence
Nature Reviews Physics 7, 331 (2025)
Programmable metasurfaces for future photonic artificial intelligence
Nature Reviews Physics 7, 331 (2025)
2024

A.T. Mok, T. Wang, S. Zhao, K.E. Kolkman, D.Wu, D.G. Ouzounov, C. Seo, C. Wu, J.R. Fetcho, C. Xu
A large field-of-view, single-cell-resolution two- and three-photon microscope for deep and wide imaging
eLight 4, 20 (2024)
A large field-of-view, single-cell-resolution two- and three-photon microscope for deep and wide imaging
eLight 4, 20 (2024)

T. Wang
A nonlinear dimension for machine learning in optical disordered media
Nature Computational Science 4, 394 - 395 (2024)
A nonlinear dimension for machine learning in optical disordered media
Nature Computational Science 4, 394 - 395 (2024)

M.G. Anderson, S.-Y. Ma, T. Wang, L.G. Wright, P.L. McMahon
Optical Transformers
Transactions on Machine Learning Research (2024) | arXiv | codebase
Optical Transformers
Transactions on Machine Learning Research (2024) | arXiv | codebase

J. Laydevant, L.G. Wright, T. Wang, P.L. McMahon
The hardware is the software
Neuron 112, 180 - 183 (2024) | arXiv
The hardware is the software
Neuron 112, 180 - 183 (2024) | arXiv
2023

T. Wang*†, M.M. Sohoni*†, L.G. Wright†, M.M. Stein, S.-Y. Ma, T. Onodera, M. Anderson, P.L. McMahon†
Image sensing with multilayer, nonlinear optical neural networks
Nature Photonics 17, 408 - 415 (2023) | arXiv | codebase
Image sensing with multilayer, nonlinear optical neural networks
Nature Photonics 17, 408 - 415 (2023) | arXiv | codebase
2022

L.G. Wright*, T. Onodera*, M.M. Stein, T. Wang, D.T. Schachter, Z. Hu, P.L. McMahon
Deep physical neural networks trained with backpropagation
Nature 601, 549 - 555 (2022) | arXiv | codebase
Deep physical neural networks trained with backpropagation
Nature 601, 549 - 555 (2022) | arXiv | codebase

K. Choe, Y. Hotani, T. Wang, E. Hebert, D.G. Ouzounov, K. Lai, A. Singh, W. Béguelin, A.M. Melnick, C. Xu
Intravital three-photon microscopy allows visualization over the entire depth of mouse lymph nodes
Nature Immunology 23, 330 - 340 (2022)
Intravital three-photon microscopy allows visualization over the entire depth of mouse lymph nodes
Nature Immunology 23, 330 - 340 (2022)

T. Wang†, S.-Y. Ma, L.G. Wright, T. Onodera, B. Richard, P.L. McMahon†
An optical neural network using less than 1 photon per multiplication
Nature Communications 13, 123 (2022) | arXiv | codebase
An optical neural network using less than 1 photon per multiplication
Nature Communications 13, 123 (2022) | arXiv | codebase

D. Sinefeld, F. Xia, M. Wang, T. Wang, C. Wu, X. Yang, H.P. Paudel, D.G. Ouzounov, T.G. Bifano, C. Xu
Three-photon adaptive optics for mouse brain imaging
Frontiers in Neuroscience 16, 880859 (2022)
Three-photon adaptive optics for mouse brain imaging
Frontiers in Neuroscience 16, 880859 (2022)
2020


S. Lee, A.J. Cortese, A. Mok, C. Wu, T. Wang, J.U. Park, C.L. Smart, S. Ghajari, D. Khilani, S. Sadeghi, Y. Ji, J.H. Goldberg, C. Xu, P.L. McEuen, and A.C. Molnar
Fabrication of Injectable Micro-Scale Opto-Electronically Transduced Electrodes (MOTEs) for Physiological Monitoring
Journal of Microelectromechanical Systems 29, 720 - 726 (2020)
Fabrication of Injectable Micro-Scale Opto-Electronically Transduced Electrodes (MOTEs) for Physiological Monitoring
Journal of Microelectromechanical Systems 29, 720 - 726 (2020)

A.J. Cortese, C.L. Smart, T. Wang, M.F. Reynolds, S.L. Norris, Y. Ji, S. Lee, A. Mok, C. Wu, F. Xia, N.I. Ellis, A.C. Molnar, C. Xu, and P.L. McEuen
Microscopic sensors using optical wireless integrated circuits
Proceedings of the National Academy of Sciences 117, 9173 - 9179 (2020)
Microscopic sensors using optical wireless integrated circuits
Proceedings of the National Academy of Sciences 117, 9173 - 9179 (2020)

T. Wang*†, C. Wu*, D.G. Ouzounov, W. Gu, F. Xia, M. Kim, X. Yang, M.R. Warden, and C. Xu†
Quantitative analysis of 1300-nm three-photon calcium imaging in the mouse brain
eLife 9, e53205 (2020) | bioRxiv | codebase
Quantitative analysis of 1300-nm three-photon calcium imaging in the mouse brain
eLife 9, e53205 (2020) | bioRxiv | codebase
2019

D.G. Ouzounov, T. Wang, C. Wu, and C. Xu
GCaMP6 ΔF/F dependence on the excitation wavelength in 3-photon and 2-photon microscopy of mouse brain activity
Biomedical Optics Express 10, 3343 - 3352 (2019)
GCaMP6 ΔF/F dependence on the excitation wavelength in 3-photon and 2-photon microscopy of mouse brain activity
Biomedical Optics Express 10, 3343 - 3352 (2019)
2018

T. Wang†, D.G. Ouzounov, C. Wu, N.G. Horton, B. Zhang, C.-H. Wu, Y. Zhang, M.J. Schnitzer, and C. Xu†
Three-photon imaging of mouse brain structure and function through the intact skull
Nature Methods 15, 789 - 792 (2018)
Three-photon imaging of mouse brain structure and function through the intact skull
Nature Methods 15, 789 - 792 (2018)
2017

D.G. Ouzounov*, T. Wang*, M. Wang, D.D. Feng, N.G. Horton, J.C. Cruz-Hernández, Y.-T. Cheng, J. Reimer, A.S. Tolias, N. Nishimura, and C. Xu
In vivo three-photon imaging of activity of GCaMP6-labeled neurons deep in intact mouse brain
Nature Methods 14, 388 - 390 (2017)
In vivo three-photon imaging of activity of GCaMP6-labeled neurons deep in intact mouse brain
Nature Methods 14, 388 - 390 (2017)

G. Rasskazov, A. Ryabtsev, K. Charan, T. Wang, C. Xu, and M. Dantus
Characterization and adaptive compression of a multi-soliton laser source
Optics Express 25, 320 - 329 (2017)
Characterization and adaptive compression of a multi-soliton laser source
Optics Express 25, 320 - 329 (2017)
2016

Y. Tang, L.G. Wright, K. Charan, T. Wang, C. Xu, and F.W. Wise
Generation of intense 100 fs solitons tunable from 2 to 4.3 μm in fluoride fiber
Optica 3, 948 - 951 (2016)
Generation of intense 100 fs solitons tunable from 2 to 4.3 μm in fluoride fiber
Optica 3, 948 - 951 (2016)